Type 1 and 2 can be
found in same individual,
says expert
Abu Dhabi, UAE
December 27 2012: A leading diabetes expert has warned about the
compounded impact and risk of rising obesity and prevalence of type 1 diabetes
in the Middle East.
In order to avoid the
nightmare scenario that he calls ‘double diabetes’, Professor Paolo Pozzilli
advised the medical community to understand how obesity is a leading risk
factor for those genetically pre-disposed to type 1 diabetes. He warned that
obesity accelerates insulin resistance and reduced insulin sensitivity, a
factor that is demonstrated to drive the immune process typical in type 1
diabetes.
Leading diabetes expert Professor Paolo Pozzilli |
“Obesity accelerates the
process known as beta cell reduction, and is a serious hazard for type 1
diabetes leading to a new observable trait or clinical entity - the presence of
type 1 and type 2 in the same individual.”
Professor Pozzilli aired his
concerns as he addressed medical experts at Imperial College London Diabetes
Centre (ICLDC) Abu Dhabi recently. Professor Pozzilli was in the capital to
share his insights on recent developments in the treatment of diabetes.
“In the region, obesity is
believed to have a major impact on the general population and in particular the
young population. Indeed, some statistics suggest that 35 per cent of school
children in the UAE are overweight or obese.”
Pozzilli is Professor of
Diabetes and Clinical Research at the Centre for Diabetes at Barts and The
London School of Medicine & Dentistry, London, as well as Professor of
Endocrinology & Metabolic Diseases at the University Campus Bio-Medico in
Rome, Italy.
He explained how the
distinction between types of diabetes is blurring as more and more factors come
to play and urged specialists to dig deep for diabetes treatment options.
“Type 1 diabetes should be
regarded as a very non-uniform disease. Until a few a years ago you had the
classification of type 1 and type 2, however now age is a factor which needs
serious consideration. I think broadly there are three ages where we have to
consider how the disease process is taking place: before puberty, during
puberty and after puberty. And the presence of insulin resistance and other
associated factors-both genetic and immunological are relevant considerations
for specialists.”
He said that early diagnosis
is crucial for managing diabetes of all types. “The earlier a patient is
diagnosed, the as less they tend to develop long term complications associated
with type 1 diabetes. Of course education is so crucial and so is compliance to
therapy,” he concluded.
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